How Excess weight might Raise Breast Cancer Risk Pure How Excess weight might Raise Breast Cancer Risk
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| Description | Women who have a certain genetic marker might be at increased risk for breast cancer, particularly if they are over weight or obese, a fresh study suggests. And if women were overweight or obese and had the marker, their risk of breast cancer increased by 210 percent, weighed against those who did not have the marker, the study found. The marker is found within a gene called mTOR, according to the scholarly study. Weight loss is likely a good way to reduce breast cancer risk generally, a research assistant professor at Roswell Park Cancer Institute in Buffalo, N.Y. If the brand new findings are confirmed by potential studies, researchers may 1 day be able to screen because of this genetic marker to recognize women that weight losswould be even more important in stopping breast tumor, Cheng said. which generally does not respond to hormonal breasts cancer treatments. White women who were obese or obese and got the genetic marker were eight times more likely to develop estrogen receptor-negative breast tumor than those who did not have the marker. The findings held even following the researchers took into account factors that could affect breast cancer risk, such as age, smoking and a grouped genealogy of breast cancer. The results suggest that being overweight or obese might promote breast cancer through variations in this gene, the researchers said. Previous studies have shown that obesity increases the risk of breast cancerfor women following menopause. The brand new study involved about 1,300 black women residing in New York and New Jersey. About half of the women within each ethnic group got breast cancer. and nearly half had been through menopause. Women were considered obese or overweight if indeed they had a BMI of 25 or greater. however, not for black women, suggesting that the result of this marker varies by ethnicity. The mTOR gene is involved in cell blood-vessel and growth formation, which are both very important to cancer growth. The gene could be active by extra energy intake, or consuming more calorie consumption than you need, Cheng said. The finding "makes sense, because, if the gene is regulated by energy intake, and women who are obese generally have excess energy intake, then that will signal the gene," which promotes cancer growth, Cheng said. The findings were presented this week at the conference of the American Association for Cancer Research. |
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